Meyers' friend Amy Poehler even got in on the mix, taking over a bit in which he would say the setup of a joke and a woman in the audience would do the punch line.
Before the show, he told Variety that he'd focusing more on Hollywood on Globes night, and said that he'd try to tread lightly and try to strike the right balance between amusing and respectful in terms of the gravity of the sexual harassment epidemic. Meyers previously hosted the 66th Emmy Awards in 2015.
It was not just another red carpet fashion showdown at the 75th Golden Globe Awards, as Hollywood's biggest and brightest stars turned up in all black to support the Time's Up movement, an anti-sexual harassment initiative.
Meyers then took aim at Golden Globe and Oscar victor Spacey. "Don't worry because he'll be back in 20 year when he becomes the first person ever booed during the In Memoriam".
Dressed in a black off-the-shoulder gown, she told E!: 'I think people are aware now of a power imbalance and that is something that leads to abuse. "Good evening, ladies and remaining gentlemen", he grinned slash grimaced, breaking the ice as best he could.More news: Bigg Boss 11, Day 99 written updates
'It's been years that a white man in Hollywood was this nervous, ' he quipped. "If it's any consolation, I'm not even the most powerful Seth in the room tonight", he said as the camera cut to Seth Rogen. Hey remember he was the guy making trouble with North Korea. Moving on to Kevin Spacey, Meyers joked that actor Christopher Plummer (who jumped in to play Spacey's part in All the Money in the World after allegations of sexual assault came to light about the actor) might be available to reshoot Spacey's scenes from House of Cards.
When the audience loudly reacted to the joke, Meyers added, "It'll sound like that".
He also mocked Spacey's Southern accent in the show, adding. Hong Chau of Downsizing then joked, "But those numbers may be off since a white man did the math".
He joked that producers asked a woman to host the show."They really did".
- "Considering what has been going on this year with powerful men and their bad behavior in Hollywood, a lot of people thought it would be more appropriate for a woman to host these awards, and they may be right".
"Give it up for the Hollywood Foreign Press, a string of three words that could not have been better created to infuriate our president", the host said later on. "The only name that would make him angrier would be the 'Hillary Mexico Salad Associated'".