The repeated injuries are weighing on Rose with a team source telling ESPN, "He's exhausted of being hurt and it's taking a toll on him mentally".
Rose hasn't played since back on November 7 as he continues to recover from a sprained left ankle.
It's been more than two weeks since Derrick Rose last suited up for the Cavs, and now there's a chance the former NBA MVP may never play again.
Last season, Rose disappeared from the New York Knicks without notification and missed a game, later saying it was related to a family matter.More news: Snoop Dogg curses out Trump in heated video defending LaVar Ball
"Just a jacked-up ankle", Rose told ESPN at the time. He was also required to wear a walking boot for the first week of that timeline.
Rose, 29, hasn't played since hurting his ankle against the Milwaukee Bucks on October 20. "So I'll wear this, for I don't know how long, to see how it helps".
Now that Thomas is nearing a return, and Dwyane Wade is succeeding as the point guard on the Cavs' second unit, it was becoming increasingly hard to see where Rose fit on this team when he did come back from injury. He was averaging 14.3 points per game in his seven games this season.
After signing a five-year, $94 million extension with the Bulls, Rose tore the ACL in his left knee during the 2012 playoffs, forcing him to miss all of the 2012-13 campaign.