And Southgate has handed first senior call-ups to three players with Swansea City striker Tammy Abraham, Liverpool defender Joe Gomez and Crystal Palace midfielder Ruben Loftus-Cheek all named in the squad after previously impressing for the U21s and their clubs.
Having been touted as being the next Big Thing while he was a youngster at Manchester United, Tom Cleverley's career at the top never really materialised as the boy from Basingstoke spent much of the last five years moving from mid-table club to mid-table club. The other guys I want to see and want to look at and that's an important part of how we want to play, building from there.
"He suffers slightly from the change of system because of the way we want to go", Southgate told reporters at Wembley on Thursday.
"That's probably the toughest call I've had to make because of the team that Chris is playing for and the fact he's playing and keeping clean sheets".
Asked if he felt Smalling was incapable of playing the ball out from the back correctly, Southgate replied: "No, I think he can".
Abraham, Loftus-Cheek and Gomez in action in the Premier League.More news: Chargers drop to 3-5 following loss to Patriots
Spurs midfielder Harry Winks was included after a fine debut in Lithuania, as was Manchester City's Fabian Delph. Until they're given the chance to do it, we won't know whether they can play at this level.
"Whether we see the benefit of that in Russian Federation or beyond Russian Federation remains to be seen".
Southgate will use the tests against the top two teams in the current Federation Internationale de Football Association rankings to hand some new players a chance to impress.
"For him, it is just about game time". "I think he'll relish the opportunity".
England play Germany on Friday, November 10, and welcome Brazil the following Tuesday. "We have spoken about Iceland, their experiences, what it felt like and why they felt like some of those things happened because when we get there again we want to be prepared for it because we've covered it".